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The Types of Non-Hodgkins Lymphoma

Lymphomas are cancers of the lymph system which ironically is part of the bodys defense mechanism to fight off infections and diseases. But sometimes the abnormal growth of the healthy lymphatic cells causes the tissues to mass up creating tumors and eventually becoming cancer cells. If left untreated, the cancer cells can easily break away from the tissues and begin infecting other parts of the lymphatic system and eventually moving to other organs of the body. There are essentially two kinds of lymphomas, the Hodgkins lymphoma and non-Hodgkins lymphoma.

Hodgkins lymphoma is characterized by the presence of Reed-Sternberg cells. Other lymphomas do not contain these cells so the rest of the lymphomas were classified as non-Hodgkin’s lymphoma or NHL. There are a number of sub-types of non-Hodgkin’s lymphoma. Each are quite distinct targeting specific age groups aside from having unique forms.

One kind of NHL is the lymphoblastic lymphoma or LBL which commonly occurs in children. In fact about 30% of documented cases of lymphomas in children have been classified as lymphoblastic lymphomas. LBL is very aggressive kind of NHL and has caused quite a number of deaths in the past. But because of modern medicine and treatment techniques, LBL patients have better odds of surviving the ordeal.

Unlike LBL, the diffuse histiocytic lymphoma type or DHL is a slow growing cancer. And because it is slow-growing the cancer is quite hard to detect. Also, there are times where the cancer reappears after treatment.

Another kind of NHL appears closer to the bodys surface. The cutaneous T-cell lymphoma or CTLC is a kind of lymphoma that affects the skin. What happens is that the white blood cells of the skin become cancerous. At first, the signs are dry, scaly skin with red or dark patches. These areas of the skin also itch a lot. But as the cancer cells continue to grow, the skin will develop highly noticeable tumors. Eventually the cancer cells enter the blood stream and spreads all over the body which soon infects other tissues and organs.

Although not common, the mantle cell lymphoma is another kind of non-Hodgkin’s lymphoma. This cancer borders on being rare since only an estimated 5% of people diagnosed with NHL have it. It seems that the cancer is more likely to occur in men 50 years old and older. The cancer starts off as a slow growing lymphoma but can suddenly become aggressive in later stages.

Doctors have made 4 classifications or stages of non-Hodgkin’s lymphoma which basically indicates how fast and how far the cancer cells have spread. Stage 1 is when the cancer cells are grouped in lymph node or organ of the body. In stage 2 the cancer has spread to two or more groups of lymph nodes or organs on the same side of your diaphragm. Stage 3 is where the cancer cells have infected organs on both sides of the diaphragm and finally stage 4 is when the different types of non-Hodgkins lymphoma have gone beyond the lymphatic system and infecting other organs like the liver, bones, and lungs.


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The Essence of PET Scans in Determining and Healing Lymphoma

The Essence of PET Scans in Determining and Healing Lymphoma

The malignant cells that cause lymphoma begin at the lymph nodes. Tumor develops when there is an enlargement of the node. The case is quite similar to lymphoid leukemia, but this only involves the bone marrow where the blood cells are produced through the haematopoesis process as well as the circulating blood.

The first description of this dreaded disease was first published in 1832. This was done by Thomas Hodgkin, thus the name of the Hodgkin type of this illness. There are many other forms that have been discovered since then and all these are now part of a large group of illnesses that are known as hematological neoplasms.

When you start feeling that you have the symptoms, especially the enlarged lymph nodes, you should seek the help of your doctor. This case may not always mean that you are sick, but to make sure that you are okay, you have to get yourself checked by a professional. The first step that doctors may require you to undergo is biopsy, the type of which will be dictated as to the organs that are infected with the disease. After it was established that you already have it, the doctors will then try to categorize from which type of this illness you are suffering from. Before you can be given proper treatment for your condition, your bone marrow needs to be tested and you have to go through various tests and scans.

PET Scans

One of the special kinds of scans that you may be asked to undergo is PET scan or Positron Emission Tomography. This is able to determine the cancers based on the high activity that is happening on the cancer cell.

Other types of scans provide different results. For example, MR type and CT scans present good quality photographs of the various body parts where you can view the masses of tumors and swollen nodes. The problem with these scans is the fact that doctors cannot based their findings whether a person has the illness based on the size and shape of what was photographed through these processes. This is what PET scans are able to fill in the blanks.

PET scans are useful in the procedure because these are used to map out the disease on a person’s body. Along with the other kinds of tests, all results can be used to determine the stages of the disease. This is also able to find out if the lump that showed up on other tests, is cancerous or not. After the condition was settled, the doctor can then proceed to give the necessary treatment, whether you need to go through chemotherapy or it will be best to undergo radiation.

After some cycles of chemotherapy, you have to go through the same scans and it will help to assess how well your body is responding to it. When the treatment has been done, you still have to go through PET scans to know whether the lump still has cancer cells, scar tissue or it has already been healed.


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Knowing Your Cancer, How Lymphoma Spreads

These are some facts according to the Leukemia & Lymphoma Society: 19.5 out of every 100,000 people in the world develop Non-Hodgkins Lymphoma while 2.8 out of every 100,000 people in the world are diagnosed with Hodgkins disease. Hodgkins disease and Non-Hodgkins Lymphoma are two of the main classifications of lymphoma, a cancer of the bodys lymph system. The lymph system, being part of our immune system, is tasked to eliminate bacteria, diseases and infection from our body. But when the cells multiply abnormally, tumors begin to appear in the lymph nodes. You can feel these as lumps in the nodes of the neck, armpit and groin. Soon the cancer cells will spread in other parts of the body, how lymphoma spreads is a good thing to know.

Metastasis. This is a word we often hear in cancer patients. This is actually a term which refers to the spreading of cancer to the rest of the body. Lymphoma at first is a single tumor in one of the many lymph nodes of the body. What happens when the cancer cells undergo metastasis is that cancer-infected cells break away from the main tumor and moves to another part of the body. The cancer cells use the bloodstream to move from one area of the body to another. The cancer cell can attach itself to another lymph node or to other organs of the body. When it fastened firmly, the cells reproduce again until it creates another mass of tissue to form as a tumor. Then the whole process repeats itself.

For lymphoma, the cancer cells use the lymphatic system of the body to spread. The lymphatic system of the body is pretty much like the bloodstream, it is spread although out the body since it is responsible for keeping the body clean from infections and diseases. The lymphatic system is an open canal where cancer cells can travel and create more tumors.

The tumors are pretty deadly. Because of the accelerated rate of growth, these cancer cells can continue to make the tumors grow. Soon enough the tumors grow large enough that the healthy tissues or organs are prevented to function normally. Eventually the healthy tissues or organs will stop functioning which spells death to the person.

Like any cancer, lymphoma has also a number of stages. These stages describe the severity of the condition and indicate how far the cancer cells have infected the body. Stage I is the first stage of the cancer. At this level, the cancer cells have only infected one lymph node or one part of the body. Because it is still developing, this stage is also referred to as the early disease.

The second stage or Stage II is far more alarming. At this point the cancer cells have metastasis and have infected another one or even more lymph nodes or parts of the body. However, at Stage II the infection is limited to either above or below the persons diaphragm. This stage is called locally advanced disease.

Stage III is known as the advanced disease. The cancer cells at this stage have found its way on both sides of the diaphragm and have established a number of tumors in those areas. The final stage or Stage IV or widespread disease is described by spread of the cancer cells to one or more of the bodys organs such as the bone, skin, liver or lungs.

This is how lymphoma spreads. That is why it is important for an early detection of the disease for proper and effective treatment.


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How Doctors Test for Lymphoma

In all kinds of diseases and ailments knowing what you have exactly can mean life and death. Identifying, categorizing and understanding your current condition allow doctors to determine the proper and most effective means of making you better. Without proper diagnosis, the prescribed treatment can be useless and at times even prove to be deadly. In the case of lymphoma, one would encounter terms like biopsy, bone marrow examination, blood tests, spinal tap and scans which are some of the basic procedures employed by medical experts to determine or confirm the presence of lymphoma.

Usually, the very first thing that helps determine if one has lymphoma is self diagnosis. Those that observe enlarged lymph nodes in the neck, armpits or groin would more often than not trigger alarm bells in the their heads. Lymphoma is a cancer of the lymph nodes and the immune system. As the cancer cells develop, a tumor is formed usually in the lymph nodes which manifests as painless lumps. Upon consultation, your doctor will issue a battery of tests to confirm if it is lymphoma and if it is indeed cancer determine what stage it is at to know the possible course of treatment.

A biopsy is usually the first test that your doctors will employ to confirm the presence of cancer in your lymph nodes. In a biopsy, a small sample of tissue cells is taken from the lump either through a needle or via surgery. The cells are then examined by a pathologist to confirm lymphoma cells and the diagnoses. By studying the sample cells, the can also determine the basic kind of lymphoma the patient has, whether its Hodgkin or Non-Hodgkin lymphoma. But to determine the subtle details, doctors revert to the procedure called as immunohistochemistry which simply means looking for the unique properties of the tumor cell surface through the application markers such as fluorescent dye, enzyme, or colloidal gold to accurately classify the tumor.

You doctor would most likely require you to undergo several blood tests. The blood samples would be examined closely to see the state of your red blood cells, white blood cells and blood platelets. These tests would also help determine if the cancer has affected your bodys way of producing blood. The blood tests could also show the condition of your kidneys and liver. And more importantly, the information gathered from the tests could serve as basic foundations for the kind of treatments or drugs that could be used for your speedy recovery.

Doctors might also require you to undergo a bone marrow test wherein a sample of the bone marrow is taken from your hip using a thin needle. It is a common procedure used to test for various cancers and other blood diseases. A spinal tap or lumbar puncture can also be ordered by your doctor in specific circumstances. This checks the fluid in your spinal cord and determines if any cancer cells have invaded the spine. This procedure involves inserting a thin needle at the lower part of your back and I can be quite painful and uncomfortable.

CT scans will also help determine where the tumors are exactly since it takes pictures of your body from different angles. An MRI scan, on the hand, will help determine if the cancer cells have spread to your nervous system or other body organs.

How doctors tests for lymphoma involves logical procedures whose main goal is finding out what exactly the patient has in order to determine what kinds of treatments would be used.


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